My research focuses on the development and application of machine learning methods for the study of cis-regulatory elements in DNA, with a focus on Polycomb/Trithorax Response Elements, a class of regulatory elements that maintain epigenetic memory.
Publications
Bredesen BA., Rehmsmeier M. (2019). DNA sequence models of genome-wide Drosophila melanogaster Polycomb binding sites improve generalization to independent Polycomb Response Elements. Nucleic Acids Res. (PubMed abstract)